Adventure Gamers has a hands on preview of The Penal Zone, the first episode of the third season of Sam & Max, The Devil's Playhouse.
The preview talks about minor plot points (but not too spoilery), increased graphic detail compared to the previous seasons, and the direct control method the game uses.
It's interesting to note that this preview is the first Telltale Games preview made by the former head of public relations at Telltale, Emily Morganti, since she left the company. She talks a bit about how different it is previewing a game from outside the company as opposed to from inside the company in her blog. It's an interesting read.